★ Fidia returns to the market with Oftalmolosa Cusí eye ointment by Icol®, suitable for the treatment of infectious conjunctivitis and non-herpetic keratitis

Fidia, A leading company in the innovation and development of hyaluronic acid products and one of the European leaders Therapeutic Solutions for the Ophthalmology Marketdedicated to the treatment of eye infections and dedicated to the market for treating these diseases Kusi Eye Drops from Icol®.

this infectious conjunctivitis It is the most common ocular infectious entity, affecting children from young children to adults, with a widespread geographic distribution.1 The number of registered cases of infectious conjunctivitis in Spain is gradually increasing every year.In newly published research, almost Cases of infectious conjunctivitis reach 400,000 in Spain.2

Among the types of eye infections, acute infectious conjunctivitis is very common. It is estimated that 50% are of bacterial origin and 50% are of viral origin.3 has been noticed Staphylococcus aureus As one of the most common causes of conjunctivitis and microbial keratitis, a vision-threatening infection of the cornea.4

Generally, this is a mild and self-limiting process.However, at most one 90% of patients receive prescribed topical antibiotics.3

To treat this type of infectious and inflammatory eye lesions, Fidia markets within its range of ophthalmic products: Kusi Eye Drops from Icol®eye ointment is suitable for infectious conjunctivitis and non-herpetic keratitis.

Khushi Eyehair Rosa from Icol® is an ophthalmic ointment containing 10 mg chloramphenicol and 0.5 mg dexamethasone sodium phosphate. This association with chloramphenicol, a broad-spectrum antibiotic, Antibacterial effectand dexamethasone, a powerful corticosteroid Antiallergic, antiexudative and antiproliferative propertiesconvert Oftalmolosa Cusí from Icol to® In products with benefit:

  • Chloramphenicol is Effective Fights against a wide variety of giant positive and negative bacteria.5-6
  • High fat solubilitywhich allows the corneal epithelium to be easily penetrated, so it may help treat deeper infections.7-9
  • Reduce chloramphenicol resistance rate More effective than any other antibiotic.10
  • Powerful anti-inflammatory. The potency and intraocular penetration of dexamethasone are sufficient to treat both external and intraocular ocular inflammation.
  • good eye tolerance And it will hardly cause any adverse effects.
  • Breastfeeding has low risks.11-12th

Likewise, Dr. Benítez del Castillo, an ophthalmologist and head of the Ocular Surface and Inflammation Unit (USIO) at the San Carlos Clinical Hospital in Madrid, said that in advantage Regarding this eye ointment, it is worth emphasizing that “Khushi Eyehair Rosa from Icol® Include Corticosteroids with greater anti-inflammatory capabilities (Dexamethasone). The anti-inflammatory potency of dexamethasone is approximately 7 times that of prednisone, so 0.5 mg/g of dexamethasone is equivalent to 3.5 mg/g of prednisone. Both ointments are effective for both extraocular inflammation and intraocular inflammation. In summary, in terms of anti-inflammatory effects, Aike Ophthalmology® It is as effective as any other eye ointment containing 0.5 mg dexamethasone or 5 mg prednisone, and is superior to all eye ointments containing hydrocortisone.“.

Therefore, the mechanism of action of this eye ointment and its consequent advantages make it a Khushi Eyehair Rosa from Icol® Very popular among ophthalmic products beneficial to treat Eye infections and inflammatory processes.

About Oftalmolosa Cusí by Icol®.

Cusí Ophasemolosa by Icol® is Eye ointments for infectious and inflammatory eye lesions, such as conjunctivitis and non-herpetic keratitis.The mechanism of action is binding Chloramphenicola broad-spectrum antibiotic with bacteriostatic effects, and dexamethasone sodium phosphate, a corticosteroid with antiallergic, antiexudative, and antiproliferative properties. This combination makes Oftalmolosa Cusí de Icol® It is a very beneficial product for treating eye infections.

For more information, see data sheet here

Bibliography: 1 . Díaz-López, MD, et al. “Microbiological Diagnosis of Ocular Infections.” Clinical Microbiology Proceedings. Madrid: SEIMC. 2019. 2. “Number of cases of infectious conjunctivitis registered in Spain from 2011 to 2016”. Published in Statista. 2019. 3 Vega, Enrique A. Criado, Laura Fuente Blancob, and Paula Ruiz. “Acute conjunctivitis (and eyelid infection).” ABE Guidelines. Pediatric infections. 2022. 4. Afzal, M.; Vijay, AK; Stapleton, F.; Willcox, MDP. Susceptibility of ocular Staphylococcus aureus to antibiotics and multipurpose antiseptic solutions. Antibiotics 2021, 10, 1203. 5. Benitez del Castillo JM, Díaz-Valle D, Gegúndez JA. Eye medication. Editor: Jaypee Brothers Medical Publishing. New Delhi. 2017.CH.12. 6. Bartlett JD, Janus SD. Clinical Ophthalmic Pharmacology. Elsevier 5th edition. Philadelphia. 2008. Page. 227-228. 7. Beasley H, Boltralick JJ, Baldwin HA. Topical application of chloramphenicol in the posterior aqueous fluid. Arches Ophthalmology. 1975;93:184e185. 8. Cagini C, Piccinelli F, Lupidi M, et al. Ocular penetration of topical antibiotics: A study of penetration of chloramphenicol, tobramycin, and netilmicin into the anterior chamber following topical administration. Clinical Experimental Ophthalmology. 2013;41:644e647. 9. Andaluz-Scher L, Medow NB. Chloramphenicol Eye Drops: Old Dog in a New House. Ophthalmology 2020;127(10):1289-1291. 10. Seal DV, Barrett SP, McGill JT. Etiology and treatment of acute bacterial infections of the external eye. Br J Ophthalmol 1982;66:357–360. eleven. Nahum GG, Ur K, Kennedy DL. Antibiotic use during pregnancy and lactation: known and unknown regarding teratogenic and toxicological risks. Obstetrics and Gynecology. year 2006. 12. Chin KG, McPherson CE 3rd, Hoffman M, Kuchta A, Mactal-Haaf C. Anti-infective drug use during breastfeeding: Part 2 – Aminoglycosides, macrolides, quinolones, sulfonamides, trimethoprim, tetracyclines, chloramphenicol, clindamycin, and metronidazole. J Hum Lact. February 2001;17(1):54-65

OFT-2023-05-September 2023

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