February 8, 2024
Between January 26 and 28, 2024, CNE notified the World Health Organization two cases Confirmed cases of human infection Avian influenza A (H5N1).These cases were reported in the region Kampong Trabekprovince Preymianand in the area Pookprovince Siem ReapCambodia.
The first case was a 3-year-old child who was diagnosed on January 26, 2024. Kampong Trabek, Prey Veng Province. The patient developed symptoms on January 13, 2024, and was admitted to the hospital on January 16, 2024 due to high fever, cough, and runny nose. Samples were collected at the hospital and transported to the National Institute of Public Health for analysis. On January 25, 2024, the sample tested positive for H5N1 by quantitative reverse transcription polymerase chain reaction (RT-qPCR) and was confirmed by the Institut Pasteur of Cambodia (IPC) on January 25, 2024. The patient had a history of exposure to outdoor activities. Dead chickens were found around the residence. A total of 14 close contacts of the case were identified, and samples were collected for analysis, and none were positive for influenza.
The second case is a 69-year-old man who died on January 28, 2024. Pook, Siem Reap Province, Cambodia. The patient had pre-existing hypertension and began to develop symptoms on January 21, 2024, including fever above 38°C, cough and difficulty breathing. The patient was admitted to the hospital on January 23, 2024, and underwent RT-PCR testing at the National Institute of Public Health on January 27, 2024, and the test result was positive for H5N1. On January 28, 2024, the sample underwent additional testing at IPC and was confirmed to be positive. According to preliminary investigations, the patient raised poultry and fighting cocks. After testing, three chickens tested positive for influenza A H5N1 virus. No environmental sampling or testing was performed. Four close contacts and 39 other contacts have been identified and tested, one of whom tested positive for the unrelated influenza B/Victoria lineage.
Since then, two confirmed cases of human infection with the H5N1 avian influenza virus have recovered. Genome sequencing and phylogenetic analysis showed that the HA genes of the A/H5 isolates from the two confirmed cases belonged to clade 2.3.2.1c.
In 2023, 6 human cases, including 4 deaths, were reported in Kampot (n=2), Prey Veng (n=3) and Svay Rieng (n=1) provinces. From 2003 to January 28, 2024, a total of 64 cases Human influenza A (H5N1) infections, including 41 deaths.
Local Risks Cambodia
More information about avian influenza in Cambodia
- The virus is endemic in birds and is excreted in large quantities in their feces. Although the risk to travelers is minimal, it is recommended to avoid direct contact with birds or their secretions. Cooked chicken does not spread the virus.
- Status report:
- 2023. Since 2005, Cambodia has had 59 cases of H5N1 infection, including 40 deaths. 2 new cases in Kampot on November 28
- 2023. In October, a girl died of H5N1 avian influenza in Prey Veng Province; in February, the H5N1 virus caused the death of a girl in Prey Veng Province
- 2022. H9N2 in Siem Reap in March.
- 2021. march. Siem Reap 1 child, 3 years old.