Postural orthostatic tachycardia syndrome (POTS) is a disorder characterized by an abnormal response of the cardiovascular system to changes in body position. When a person with POTS stands, most of the blood remains in the lower body, causing the heart rate to increase rapidly. POTS is a complex disease with a range of symptoms affecting various body systems. Diagnosis and management require a multidisciplinary approach, including medical, lifestyle and emotional interventions, to improve the quality of life of those affected by the disease.
POTS can cause a variety of symptoms, including:
These symptoms often worsen during activities such as showering, standing in line, or being stressed. Additionally, POTS symptoms may be triggered after eating because digestion requires increased intestinal blood flow.
Certain factors make individuals more susceptible to POTS, including:
Prevalence among women aged 15 to 50 years. Although no single gene has been found, a genetic link may exist. Associated with a variety of conditions, such as anemia, autoimmune diseases (such as Sjogren’s syndrome or lupus), chronic fatigue syndrome, diabetes, Ehlers-Danlos syndrome, infectious diseases (mononucleosis, Lyme disease , hepatitis C), multiple sclerosis, and click murmur syndrome (mitral valve prolapse). POTS can also occur after a serious infection, pregnancy, or head injury.
Diagnosing POTS can be challenging because of the variety of symptoms of POTS. The tilt table test is a commonly used diagnostic method. In this test, patients lie on a table that is slowly tilted upright to simulate standing while their heart rate changes are monitored. It is important to work with an expert who is familiar with POTS. Other tests may include urine tests, blood tests, electrocardiogram, echocardiogram, quantitative sudomotor axon reflex test (QSART), Valsalva maneuver, and cutaneous nerve biopsy.
Although there is no cure for POTS, a variety of treatments can help manage its symptoms:
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