Scientists hope to create mutant chickens to prevent bird flu

In one study, researchers edited a protein in birds and, as a result, nine out of 10 birds showed resistance to bird flu.Horse racing details

Barbara Giovanni

6 minutes ago

According to a new study published in the journal nature communicationsBird gene editing may curb the spread of avian influenza.Currently, the world is going through many difficulties in stock Already registered doença.

Generally, the risk of human-to-human transmission of avian influenza is low. More authorities are concerned as they report that more mammals are contaminated this time, such as guarcinins, fur seals, olive ridley turtles and more.

The second or map (Ministry of Agriculture, Pecuária e Supply), now the forum has confirmed the neighborhood 139 kitchen lights There is no Brazil.According to the data, if cases or situations expand in the country, or prejudice could reach as much as 2.2 billion reais FGV investigation.

genetic solutions

The virus that is circulating is H5N1, known since 1996 and considered to be highly pathogenic. Currently, vaccination of animals is the main method to prevent epidemics. Avian Influenza.

However, the disease’s virus evolves rapidly, making existing vaccines less effective over time. In addition, there are many strains of avian influenza viruses, but vaccines are only effective against specific strains.

That way, investigators look for more permanent solutions. They proposed gene editing to alter a specific protein (ANP32A) in the bird organism that is essential for the propagation of all variants in the virus. Avian Influenza.

Generally speaking, scientists stress that this process is not genetic modification—it involves the transfer of genes from one species to another. What we present is new research into gene editing using well-known molecular technologies such as CRISPR/Cas9.

Because gene-edited birds mature without adverse effects on their health.

Once completed, the researchers say, gene editing could occur naturally in our descendants. And, when you are exposed to a virus, Avian Influenza9 out of 10 people will show total resistance.

Next, we also found that the virus was able to adapt using edited ANP32A proteins and other related dyads. “But we showed through cell experiments that editing three proteins simultaneously can completely suppress the virus,” he explained. Arewo Idoko Akoauthor of the study.

Now, research is underway to identify the specific gene editing combinations needed to create the next generation of bird flu-resistant chickens.

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