Antibiotic-resistant infections are becoming increasingly common. They range from skin infections caused by Staphylococcus (staphylococcus) bacteria, to sexually transmitted infections like gonorrhea, to a variety of illnesses caused by Klebsiella pneumoniae, including pneumonia. When an infection doesn’t respond…
Antibiotic-resistant infections are becoming increasingly common and include skin infections caused by staph, sexually transmitted infections such as gonorrhea, and a variety of illnesses caused by bacteria. Klebsiella pneumoniae including pneumonia. When an infection doesn’t respond to treatment, it can spread throughout the body.
Antimicrobial resistance (AMR) begins primarily in bacteria and viruses that live in the body, skin and environment They learn to avoid antibiotics and antiviral drugs. This affects the entire health care sector. It can cause infections that lead to hospitalization, may worsen the condition of people already hospitalized, and can be fatal for people with compromised immune systems (such as children and the elderly), people with cancer, organ transplants, etc. .
“This is a slow-moving disaster“He emphasized that in this regard, David van Duyne, Professor of Infectious Diseases at the University of North Carolina School of Medicine (SOM). ““People are just beginning to accept that antimicrobial resistance is getting worse, but it’s an existential threat to everything we do in medicine.”.
A multidisciplinary approach is needed
Solutions to so-called ‘superbugs’ needed A multidisciplinary approach because of its wide-ranging impact. The main goal is to study how antimicrobial resistance works and educate healthcare professionals on the correct use of antibiotics to stop more drug-resistant infections from developing.
Van Duin is part of a project from the Institute for Global Health and Infectious Diseases (USA), in collaboration with researchers at the University of North Carolina at Chapel Hill, focusing on Key areas: Provide new guidelines for antibiotic use; reduce the spread of infection by developing better health infrastructure and practicing hygiene; and learn to better identify ADRs to inform treatment.
Another important risk factor is changes in Earth’s climate. Bacteria and viruses grow faster and stronger at higher temperatures.and natural disasters causing unsanitary conditions and increased pollution, andExposing people to more potential superbugs. From these researchers’ perspective, monitoring antimicrobial resistance after an event such as a hurricane or earthquake provides another opportunity to gain information. In this regard, the researchers found that across all countries, antimicrobial resistance was more severe in areas with fewer resources.
new treatment
In this field, Brian Conlon and his laboratory SOM Department of Microbiology and Immunology (USA) focuses on alternative strategies for treating infections with existing antibiotics. It aims to make previously ineffective treatments work better by controlling how treatments are delivered at the microbial level and reversing antimicrobial resistance by coaxing bacteria to respond to the drugs.
They are also looking at how diabetes, which affects more than one in 10 people, affects treatment. “There is evidence in mouse models that antibiotics are less effective when diabetes is present, which is concerning because diabetes is increasingly common in the United States.Conlon said. The challenge for Conlon is to find a way Complete elimination of drug-resistant pathogens from patients Medication, but with current treatments, he believes “it’s almost impossible.” “Sometimes the culprit is a person’s own immune system“I came to the conclusion