What it is used for, how to take it and side effects

Phenapiridine is a urinary tract analgesic used to relieve pain or discomfort from irritation of the urinary tract that may result from urinary tract infection, trauma, surgery, or medical procedures such as placement of a bladder catheter. example.

This medicine can be found in pharmacies in tablet form containing 100 mg or 200 mg of phenazopyridine hydrochloride under the trade names Macrodantina, Futroken, Ircilus, Furadantina, Biofurin, Macrofurin, Urofuran, Zuvic or Nitrocare and sold as an introductory medical prescription.

Phenapiridine is indicated for use in adults only and should be used under medical supervision after evaluating the cause of painful and uncomfortable urination symptoms and the presence of a urinary tract infection.

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what is this for

Phenapiridine relieves pain, burning, and discomfort when urinating if:

  • urinary infections;
  • Urinary Trauma;
  • Urinary system surgery;
  • Endoscopy of the urinary tract, such as cystoscopy or urethrocystoscopy;
  • Placement of a urinary or bladder catheter;
  • In the case of a urinary tract infection, this medication may be prescribed to supplement doctor-prescribed antibiotic treatment, as it can reduce pain and discomfort when urinating until the antibiotics are able to clear up the infection.

Phenazopyridine acts directly on the urinary tract and, due to its analgesic effect, reduces pain, burning and discomfort during urination, as well as the urge to urinate.

how to drink

Phenapiridine should be taken orally with a glass of water, preferably after a meal to reduce stomach irritation.

The usual recommended dose for adults is 200 mg every 8 hours as follows:

  • Phenazopyridine 100 mg tablet: Take 2 tablets of 100 mg every 8 hours. The maximum daily dose is 6 tablets of 100 mg within 24 hours, taken in divided doses;
  • Phenazopyridine 200 mg tablet: Take 1 tablet of 200 mg every 8 hours. The maximum daily dose is 3 tablets of 200 mg in divided doses within 24 hours.

Use of phenazopyridine in the elderly should only be done under medical supervision, as dose adjustments may be required due to greater impairment of renal function.

When used with antibiotics to treat UTIs, phenazopyridine should be taken for up to 2 days.

If you forget to take your medicine, take it as soon as you remember. But if it is close to your next dose, you should skip the missed dose and wait for your next scheduled dose. Under no circumstances should the dose be doubled to make up for a forgotten dose.

Care during or during treatment

During treatment with phenazopyridine it is important to consider some precautions such as:

  • Take the medicine at the recommended time and during the treatment period prescribed by the doctor;
  • drink enough fluids during treatment;
  • Avoid wearing gel contact lenses during treatment, as phenazopyridine can cause lens staining;
  • Take the tablets as soon as you put them in your mouth, as keeping them in your mouth can cause staining of your teeth.

In addition, if patients are undergoing urine testing, they should inform the laboratory that they are taking phenazopyridine because this drug can interfere with the results of colorimetric, spectrophotometric, or fluorescent urine tests.

side effect

The most common side effects of phenazopyridine treatment are stomach irritation or discomfort, dizziness, headache, nausea, vomiting, diarrhea, itching, or rash.

In addition, phenazopyridine can cause urine and stool to turn reddish-orange, which is common during treatment because of the presence of a dye in its composition, although this is more rare, other body fluids and tissues can also have this effect . Color, such as nails, lips, or sperm.

Phenapiridine may also cause more serious side effects that should be reported to your doctor right away, such as little or no urination, swelling or rapid weight gain, loss of appetite, low back pain, confusion, abdominal pain, fever, pale, yellowish skin , blue or purple.

This drug can also cause a serious allergic reaction that requires immediate medical attention. Therefore, if symptoms such as shortness of breath, coughing, throat tightness, swelling of the mouth, tongue or face occur, treatment should be discontinued and emergency treatment should be sought at the nearest hospital. Learn how to recognize the symptoms of a severe allergic reaction.


Children, pregnant or nursing women, or people with severe renal or hepatic impairment or who are allergic to any ingredient in the formula should not use phenazopyridine.

Also, people with glucose-6-phosphate dehydrogenase (G6PD) enzyme deficiency should use this drug with caution because it may cause hemolytic anemia.

Diabetics should also use phenazopyridine with caution because this tablet contains sugar in its ingredients.

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