First PhD thesis on COVID-19 demonstrates effectiveness of corticosteroid treatment

A researcher from University of Granada and San Cecilio Hospital The first PhD thesis in Spain on SARS-CoV-2, the virus that causes Covid-19, was defended by analyzing the effectiveness of the following method corticosteroid treatment Patients with moderate or severe pneumonia.


The author, Ismael Francisco Aomar, also a physician, was living on the front lines of the hospital’s fight against the coronavirus in March 2020, UGR reported in a statement on Wednesday.

In the paper, which Omar completed while continually seeing coronavirus patients in the hospital, he showed that anakinra, a drug used to combat inflammatory diseases such as Still’s disease in adults . Effectively improve the prognosis of pneumonia patients Hospitalization with moderate or severe SARS-COV-2.

It has also greatly reduced people’s income Intensive Care Unit (ICU), as long as it is used early with corticosteroids.


In March 2020, the new doctor treated Granada’s first coronavirus patients during a shift at the San Cecilio Clinical Hospital.

“We have never seen anything like this before, where we were all blindly treating at the beginning. In fact, drugs like hydroxychloroquine or azithromycin are currently treating large numbers of Covid-19 patients. “They are not suitable for these patients.”he pointed out.

The San Cecilio Clinical Hospital in Granada was one of the pioneers in using anakinra as a rescue treatment during the 16 months of analysis of coronavirus patients with all symptoms All come from anakinra. Other medications have no effect.

Although a sample of 10 patients was included in his doctoral thesis, his research work subsequently continued and is now Samples from more than 300 patients have been analyzedthey respond very well to anakinra treatment.


Among the advantages of this drug, the most prominent are It has a very good safety profile with a half-life of about six hoursSide effects were also minimal compared with three weeks of other immune modulators that have also been successfully used to treat excessive inflammation in covid-19 pneumonia.

The first doctoral thesis on coronavirus in Spain was supervised by Dr. José Luis Callejas of the San Cecilio Clinical Hospital and Francisco Javier Gómez Jiménez, professor of the UGR School of Medicine.

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