HPR Volume 17 Issue 12: News (October 16, 2023)

NHS Blood and Transplant Annual Report and british health and safety agency epidemiology group

The latest annual report from the NHS Blood and Transplant Joint Agency (NHS) and the UK Health Safety Authority (british health and safety agency) Epidemiology Unit, “Safe Supply 2022: Monitoring Donor and Recipient Safety,” published in NHS website.

joint NHS and british health and safety agency The Epidemiology Unit was established in 1995 and is responsible for monitoring infections in blood, tissue and organ donors and transfusion recipients, collating epidemiological data on blood-borne infections among donors, and assessing the risks associated with transmission through transfusion and transplantation .The unit consists of a small team of epidemiologists and public health experts who work with scientific and clinical colleagues NHS and british health and safety agency.

The 2022 annual review shows that infection numbers remain low across all donor groups, supporting good compliance with donor selection. Blood donation numbers continued to increase in 2022 compared to 2020 and 2021; a total of 1.8 million donations were made by 950,000 donors across the UK, with a small number of donations being removed from the supply due to reactions.

Approximately 271 donations (1 in 6,500 donations) were confirmed positive for hepatitis B virus (Hepatitis B virus), hepatitis C virus, HIV, human T-lymphotropic virus or syphilis and discarded, similar to 2021.There were 130 viral infections and 142 syphilis infections, including 1 double infection Hepatitis B virus and syphilis infection. Most of the cases removed were new donors, most of whom were long-term infected, with the number of infections increasing since January 2021 – donors who were permanently withdrawn from donating.In addition, 368 donations (1 in every 4,700 donations) were discarded after being confirmed positive for hepatitis E RNAalso similar to 2021.

this Fair Donor selection policy that allows gay, bisexual and other men who have sex with men (GBMSM) Donating blood in the UK from June 2021 will not affect the safety of the UK blood supply: no recent infection with hepatitis B, hepatitis C or HIV Infection rates during routine screening remain below one per million.

Confirmed positive donors demonstrate good compliance Fair Policy standards that help maintain security. Of confirmed positive donors, 80% met donor selection criteria, similar to 2021 compliance levels.

The UK will begin routine blood donation screening for hepatitis B core antibodies in 2022, after ministers accepted recommendations from the Advisory Committee on the Safety of Blood Tissues and Organs (SaBTO). This has had an impact on increasing detection of potentially infectious HBV from donors with latent HBV.

NHS Run a clear risk assessment and action process to identify potential risks to the UK’s blood and tissue supply, including horizontal scanning for outbreaks, new and re-emerging infections. In May 2022, a monkeypox outbreak was detected by Horizon Scan to conduct a risk assessment of potential new threats to blood safety.work closely with british health and safety agency Colleagues, the joint unit conducted a blood safety risk assessment and concluded that by providing donors with pre-donation information and existing mitigation measures, including Fair Donor Selection Policy.

transfusion-transmitted infections (TTIIt remains extremely rare in the UK due to risk reduction strategies including donor selection and rigorous testing of blood donations.All are suspected TTI The British Blood Service investigation has been reported to NHS and british health and safety agency Epidemiology departments are responsible for monitoring and forming part of the serious hazards of blood transfusions (shooting) Hemovigilance Program. 2022 shooting The report will be released in July 2023 and will be available via shooting website.

During 2022, British Blood Services investigated 115 suspected bacterial incidents, 1 suspected parasitic incident and 8 suspected viral incidents.A viral incident was diagnosed as hepatitis B virus TT Involves 2 containers: with shootingwhich was identified as the first confirmed hepatitis B transmission from a donor with occult hepatitis B infection (Obi) in England. The transfusion occurred in 2021, before the introduction of hepatitis B core antibody testing.

Between 2018 and 2022, TT Investigation conclusion 4 confirmed (1 Hepatitis B virus1 Hepatitis B virus Review and 2 Hepatitis E Virus (hybrid electric vehicle) review) and 4 possible (3 Hepatitis B virus and 1 hybrid electric vehicle)transmission.all Hepatitis B virus TTI from donor Obi. The rate of bacterial contamination identified in platelets was very low, with only a small number of clinically relevant bacteria found.Recently confirmed bacteria TT It was in 2015.

Evidence of Creutzfeldt-Jakob disease (CJD) Transfusion transmission was collected through the Transfusion Medicine Epidemiology Review (TMER) in collaboration with the National Institutes of Health CJD Research and Monitoring Department established since 1997. The number of cases is small and rarely related to the blood supply. In 2018, the risk level was downgraded and plasma collection for UK manufacturing could safely restart. US and Australia scrap extensions for those who have spent time in UK in 2022 Creutzfeldt-Jakob disease It broke out from 1980 to 1996.

In collaboration with Imperial College London, we continue to recruit and curate a national registry of human T-cell lymphovirus (HTLV). Health information reported by participants at the eighth follow-up visit in late 2022 (mainly asymptomatic blood donors) showed that episodes of serious illness were rare.

Organ donations from deceased donors increased in 2022 compared to annual data for 2020 and 2021. However, the number of consenting donors has not yet returned to pre-pandemic levels. Consenting donors were tested for pathogen reactivity, and no donor-derived transmission was recorded in 2022. NHS Programs that also manage living and deceased tissue donors and cord blood donors, with protocols similar to those for blood donors, often identify only a few infection markers, often due to previously unrecognized chronic infections.

complete NHS and british health and safety agency A PDF of the 2022 Epidemiology Unit Report is available at NHS website.

For a detailed summary of all monitoring program data for the unit please send to: epidemiology@nhsbt.nhs.uk

Full year 2022 complete shooting The report is available in PDF format at shooting website.

british health and safety agency Begin publishing detailed weekly influenza and COVID-19 surveillance reports

british health and safety agency The detailed National Influenza and COVID-19 Surveillance Report, which provides the latest summary information on the levels of influenza and COVID-19 activity in the UK population, has started to be published every week (Thursday).

Weekly reports include graphical presentations of detailed epidemiological and virological data generated by various national surveillance programmes. The first weekly report is based on data from Winter Week 40 (October 2-8) of 2023-2024.

Health professionals can subscribe to the weekly email (including summaries and links to key reports and relevant documents) by sending their name and email address to: respscidsc@ukhsa.gov.uk

Infection report in this issue

Reports of respiratory tract infections british health and safety agency Desde british health and safety agency NHS laboratories in England and Wales: weeks 33 to 37 2023

National acute hepatitis B enhanced surveillance report (England): January to December 2021

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