New study finds neck scarring acne and primary scarring alopecia share common precursor conditions

angels, September 5, 2023 /PRNewswire-Spain/ — Researchers at Dr. U, a hair and skin clinic in Los Angeles, have discovered a fundamental relationship between two medical problems: scarring acne of the neck and primary scarring alopecia (commonly known as scarring alopecia). sexual alopecia). The findings, published in the journal Clinical Cosmetology and Dermatology Research and titled “Uncovering common precursors to nuchal keloids and primary cicatricial alopecia,” have important implications for diagnosis and treatment.

Researchers have linked all common scarring alopecia to a single-root condition called PIILIF (perifollicular infundibular lymphocytic infiltration and fibrosis).

Nuchal keloid acne (NCA) belongs to a group of scalp disorders known as scarring alopecia, a condition known for chronic inflammation that causes scarring alopecia with pain, discharge, itching, and decreased social ability. AKN often produces disfiguring keloid-like lesions. Hidden relationships and shared root conditions are investigated.

Traditionally, AKN and scarring alopecia have been studied separately. This study revealed a relationship called “perifollicular infundibular isthmus lymphocytic infiltration fibrosis” (PIILIF), which is found in the normal scalp area (NAS) of all AKN patients. PIILIF can reveal the early stages of AKN and scarring alopecia. doctor. Sanusi UmarThe study’s lead researcher, chief of the Section of Scalp and Hair Diseases in the Department of Dermatology at Harbor-UCLA, emphasized that the findings suggest there may be more precise treatments to address the underlying causes and refine diagnostic strategies.

Dr. Umar explained: “Our findings, along with other studies, suggest that PIILIF may be involved in all common scarring alopecias, such as AKN, folliculitis alopecia (FD), lichen planopilaris (LPP), frontal fibrosing alopecia, and Scarring Alopecia. Centrifuge. This highlights their interconnectedness, provides new insights into their origins, and allows for more comprehensive diagnostic and treatment strategies. Furthermore, this could be achieved by reducing redundancy in closely related conditions Simplifying the complex classification of scarring alopecia. For example, our study questions the necessity of the entity currently designated as the LPP-FD phenotype.”

Surprisingly, the study found that AKN is more common in white people of European ancestry (10% of patients) than previously thought, and is often unrecognized or misdiagnosed as nape irritation or dandruff. This finding challenges the perception that AQN only affects people of color.

This research is important because it could reshape our understanding of AKN, scarring alopecia, and treatment. More research should be conducted to discover the mechanisms, triggers and role of PIILIF in hair loss. However, this work paves the way for improved diagnosis, treatment and well-being for patients.

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Sara Harutunyan
Hair and Skin Clinic, Dr. U

Dr. U Hair and Skin Clinic (PRNewsfoto/Dr. U Hair and Skin Clinic)


SOURCE Dr. U Hair and Skin Clinic

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