The number of cancer drugs being studied has increased by 75% in the past 8 years

A researcher works at the new Experimental Oncology Center at the 12 de Octubre University Hospital Research Institute in Madrid, Spain. (Gustavo Valiente – European Publishing House)

this cancer research is the key to progress in the fight against this series of diseases Affects 20 million people every year and cause 10 million people died.

This is a complex process in which researchers from both the public and private sectors from around the world are also depends on Involvement of cancer patients, Cancer survivors and healthy volunteers, providing data and resources to make progress in the fight against this disease.

this sunday September 24th is World Cancer Research Day Encourage the 3,500 existing research areas, of which approximately 2,000 products are in the clinical research stage.

Ranolazine increases the number of antitumor lymphocytes (green). (Image source: IN-IRB-Navarrabiomed. Image provided by CSIC. EFE)

Cancer research leads to new discoveries, e.g. new medicine cure cancer, New treatment to relieve severe symptomsor make lifestyle changes to reduce your chance of getting cancer.

Cancer research also helps answer a wide range of other questions, such as Why cancer affects certain groups more Or what doctors can do to improve the effectiveness of health center screening methods. These findings help cancer patients and their caregivers live more fulfilling lives.

In that framework, CAEMEthis argentine medical professional associationRepresenting pharmaceutical and biopharmaceutical companies that research, develop and market innovative medicines in the country, highlighted how Cancer Research and Development Given that more than 200 different types of cancer have been discovered to date, we have successfully transformed the impact of this disease, or rather, a range of diseases.

New tools in the fight against cancer focus on targeted therapies, immunotherapies, and cell or gene therapies. (EFE/Katicladra)

doctor Suzanne BaldiniThe CAEME medical director explained that recent research “has led to the development of increasingly effective and safe treatments, and Best ways to care for cancer patients, always with the goal of improving their survival rate and quality of life, with the biggest goal being to cure the disease or make it a chronic disease. “

In addition to the fact that many cancer cases are not linked to risk factors, according to experts, Preventable risks, more research on cancer suggests up to 50% of cases in the case of This can be avoided by leading a healthy lifestyle: physical activity, a varied and balanced diet, limited or no alcohol consumption, zero tobacco use, no exposure to the sun at harmful times and the use of sunscreen.

“Today we know that almost half of all cancer cases can be prevented by these measures. Another equally powerful measure is to keep vaccination programs up to date, because in this way many cases Liver cancer secondary to hepatitis B, For example, preventing cervical cancer through the HPV vaccine,” he said. Baldini.

Comparison of healthy cells (i) and damaged cells (d) during the replication phase. (EFE/Ospedale Pediatrico Bambino Gesù)

On the other hand, scientific innovation also enables the realization of The average survival rate for people diagnosed with cancer is 50%, Not long ago there were things that would have been unimaginable.

In addition, great progress has been made in recent years in the development of drugs for the late or metastatic stages of certain types of cancer, significantly extending people’s lives.

It is important for doctors to be able to identify the origin of cancers of unknown primary so that the most effective treatments can be used.

Science looks at what doctors can do to make screening methods more effective (Institute for Biomedical Issues)

this immunochemistry and other laboratory tests are very useful for this purpose, but these tests are still Unable to indicate where all cancers of unknown primary origin begin. The new laboratory test, along with others currently under investigation, will help more accurately classify cancers of unknown primary origin and help predict patient prognosis and response to treatment.

It is expected that at some point in the future, as doctors can test tumor samples and determine the type of cancer, the number of cancers of unknown primary will decrease significantly.

this Oncology clinical activities It represents the majority of R&D activities in the pharmaceutical industry and has innovated on many novel models. Over the past decade, there has been increasing interest in therapies with specific and innovative mechanisms of action.

It is estimated that by 2040, there will be 29.5 million cancer cases annually worldwide (EFE)

he 75% of oncology trials will start in 2022 Evaluating potential therapies for solid tumors.Likewise, although the proportion of oncohematology trials is small, these trials Increased by 30% between 2017 and 2022, More than 550 trials are starting in 2022. Most oncology trials focus on rare cancers (56% of them starting in 2022).

Currently, according to CAEME internal survey data, of all clinical studies ongoing in my country, 25.4% are studying molecules of different types of solid tumors, and 6.3% are studying molecules of tumor and blood diseases.

An untreated tumor (left) compared to another tumor treated with the CRISPR gene-editing system (right) – EFE

“Perhaps the most innovative are the different mechanisms of action or highly advanced classes of treatments that are already available or in development, based on Targeted therapy, immunotherapy, cell or gene therapy (There are about 500 such vaccines in development, and there are even preventive and therapeutic vaccines based on platforms such as messenger RNA, which make it possible to develop a vaccine against COVID-19,” he stressed. Baldini.

expected By 2040, there will be 29.5 million cancer cases worldwide each year. However, due to the impact of cancer research, the National Cancer Institute predicts that by 2030, there will be 22.2 million cancer survivors in the world.

“The escalating progress recorded recently makes us optimistic about the near future. We believe we are getting closer every day to mitigating this scourge. There is still a long way to go, so we must continue to shed light on the different people involved work to find answers to ongoing unmet needs because we know the impact of cancer on a person’s life, the environment as a whole, and the burden it places on society as a whole,” CAEME concluded.

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