Cofepris warns of health risks from use of ‘poppers’ | Federal Council for the Prevention of Health Risks | Government

  • They contain chemicals that are highly toxic, volatile and even flammable.
  • They can cause eye damage and vision loss.
  • Its addictive potential represents a risk of intoxication from overdose.
  • Increased likelihood of heart attack

Mexico City, September 18, 2023. – Federal Council for Protection against Health Risks (Cofepris) Alert about consuming “poppers” products, Used for recreational purposes because, in addition to their addictive properties, they contain highly toxic, irritating, volatile and flammable chemicals.

Cofepris found that these products, which are typically sold in liquid form and packaged in vials for inhalation, have become popular among youth and adolescents.

Some uses of “poppers” are as psychoactive substances and/or sexual stimulants. These products produce a state of euphoria and non-inhibition, which may increase unsafe sex, leading to the acquisition of sexually transmitted infections (STIs).

Consumer tolerance to these products is one of the biggest dangers. Because of its short duration of action, people need higher doses, which increases the risk of poisoning from overdose and the risk of suffering adverse effects, the most common of which are dizziness, vomiting, a drop in blood pressure, or tachycardia.

Other possible health effects of consuming “poppers” include: respiratory tract irritation, causing difficulty breathing; chronic cough; bronchitis; and lipoid pneumonia. It can also cause eye injuries, vision impairment, and in some cases, vision loss.

Likewise, long-term abuse of this substance has been found to affect peripheral nerves, causing muscle weakness, numbness, and difficulty with movement coordination. In addition, they can negatively impact the cardiovascular system, causing a drop in blood pressure, tachycardia, arrhythmias, ventricular fibrillation, and even an increased risk of heart attack.

Concomitant use of “poppers” with other stimulant drugs (such as ecstasy, methamphetamine, and cocaine) or medications (drugs that prolong erections or treat high blood pressure) may put additional stress on the cardiovascular system, the more intense this stress. The more intense and dangerous it becomes. The dosage and frequency of use of these substances.

The compounds found in these products are amyl nitrite, isobutyl nitrite, isopropyl nitrite, or butyl nitrite, which are characterized by a colorless liquid in some cases and a yellow color in others. Additionally, they are toxic, irritating, highly volatile and flammable.

Let’s share the characteristics and chemical safety of nitrite contained in “popcorn”:



chemical safety

Amyl nitrite

Despite its fruity, aromatic and penetrating taste, it is harmful if ingested and inhaled.



Isopropyl nitrite

Toxic in contact with skin and if ingested. It can cause severe skin burns, eye damage and respiratory irritation.



acute toxicity irritation

Butyl nitrite

Even though its aroma is pleasant, it can be toxic if ingested and inhaled. It is used to make fuel for jet aircraft.


acute poisoning

Isobutyl nitrite

Its intake is harmful.Acute toxicity warning if inhaled



Cofepris therefore advises the general population not to acquire or use these substances and to avoid combining them with other legal or illegal substances as their consumption may pose health risks.

If you see a product with the characteristics shown, do not purchase the product and for information about possible marketing, please file an appropriate health complaint online: Or call 800 033 5050.

Likewise, the National Council on Mental Health and Addiction (Conasama) is reported to be available through Addiction Primary Care Centres, AC Adolescent Integration Centres, Health Centres, Community Mental Health Centres, Integrated Mental Health Centres, or by calling Lifeline 800 911 2000. information.

Cofepris continues to carry out health surveillance operations to prevent products, companies or institutions that do not comply with current health legislation and pose risks to population health.


This alert is issued for dissemination purposes only and is directed at the general population, so it does not represent a resolution authorizing, extending, revoking the health authorization, nor does it represent a clear statement concerning the imminent imposition of administrative sanctions or preventive or corrective measures. Security measures.

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